Winstone's credits include the films Bullet Boy (2004), Daddy's Girl, Kidulthood (both 2006) and Donkey Punch (2008), the television series M.I.T.:Murder Investigation Team, Vincent (alongside her father), Totally Frank, Goldplated and Dead Set and a short film called Love Letters. She was cast in a BBC pilot Phoo Action, but a planned series was cancelled just as filming was about to start.
Winstone sings backing vocals for her sister Lois' band. As an actress she has appeared in the music video