Brammall was born in Canberra.[2] He was born with the rare genetic disorder prune belly syndrome and his doctors did not think he would survive. He underwent several operations and spent quite a lot of time in and out of hospital during the first 10 years of his life.
Patrick Brammall graduated from VCA in 2001.[4] His breakthrough role was in the 2004 television movie The Alice, which led to a starring role in the spin-off series in 2005. He also had a starring role in television series Canal R