Fatima Sana Shaikh was born in Hyderabad, India, to Hindu Brahman Father, Vipan Sharma, and Muslim Mother, Raj Tabassum. At an early age, she moved to Mumbai, which became her hometown since. She was enrolled to St. Xavier High School in Mumbai for her primary education and later to Mithibai College, Mumbai for higher education.
Shaikh began her film career with the 1997 film Chachi 420 with Kamal Hasan. She played the role of Bharti, Jaiprakash Paswan a.k.a. Jai and Janki Paswan's daughter. Thou