本系列节目在全球Discovery频道播映，影片用记录片的形式，以真实案件为原型，详细描写了办案人员侦破各种疑难案件的过程及所用各项科学技术。案件内容由演员按照事发情况模拟演出，情节逼真，办案人员的巧思和努力令人赞叹。
        Forensic scientists work with a variety of methods (i.e. computer technology, anthropology, entomology) to solve crimes which would otherwise remain unsolved, through finding seemingly obscure clues such as tire tracks, bullet fragments and hair samples and then putting the pieces together. Interviews with forensic pathologists, cold case detectives and victims families show the process entailed in each case. Three separate cases are spotlighted in each episode of this series.